疾病往往使人身心憔悴，但這並不能阻止Louise Wedderburn與Stephen Thompson圓夢。自小就與眾不同，兩位模特兒靠著超人的意志力，打破他人歧視眼光，並極力與病痛抗爭，努力邁向時尚頂端，成為備受時尚界關心的模特兒們。
在2011年，因疾病纏身而聞名時尚界的當紅模特兒Stephen Thompson，是一位擁有白化症的美國男性模特兒。在Givenchy 2011秋冬時裝秀中首次露面的他，陸續出現在Givenchy 2011春夏廣告中，是設計師Riccardo Tisci的愛將之一。擁有滿頭白髮及蒼白的皮膚，設計師幫他打造一身歌德裝扮，走出伸展台不一樣的極端，而對於Stephen Thompson，Riccardo Tisci曾表示：「他們就是很接近我的世界，Stephen的神祕魅力是一種時尚缺陷美，他能幫助我的設計提昇層次。」並運用不一樣的視點，以時尚包容了與眾不同的Stephen Thompson。
另一位勇敢在時尚圈克服疾病的模特兒是年僅19的Louise Wedderburn。出生於英國倫敦的她，在3歲時便發現自己患有罕見遺傳疾病「肌肉骨化症」，不但目前無藥可救，因肌肉組織會隨著年齡增長漸漸骨化，可能只活到41歲就會全身僵硬到無法動彈。但是她從向像病魔低頭，從小想成為模特兒的她，不放棄自己的夢想，終於透過設計師Nadine Merabi的幫忙，踏上2013倫敦春夏時裝週的舞台，並登上11月號的＜Elle＞。同月，英國拍攝了一部有關Louise Wedderburn的紀錄片「人類模型」在第四台播出，引起強大迴響，希望時尚界能多給她一點機會，讓她能開心走完短暫的一生。
»»Within the fashion world, there are weird things happening due to the eccentricity of the behavior of fashion. While a super model who stuns in his or her own gender is nothing new in fashion, the unisexual, or Androgyny, is the new trend of modeling, showing the world how open minded fashion is. Further, there are models with sickness are also accepted in fashion, or praised even, to let the world know how fashion also spreads love to those who needed it.
In the new generation, aside from Andrej Pejic, there are also few names we need to know for the Androgyny model: Stas Fedyanin and Stav Strashko. While Stas Fedyanin has been a teen model since he was little, he has always shined in fashion photography. As a model of Dopamin Models, he has a great amount of fans and a lovable girlfriend. With Andrej Pejic open up the road of fashion for him, he told the press that fashion does fascinates him, but since he’s only 17 years old, he still have lots of dreams to pursue. On the other hand, Stav Strashko got his fame from the Japanese Toyota Auris commercial. As a Ukraine model who grew up in Israel, he has a face and curve of woman but a body of man. When he was interviewed by Candy magazine, he told the media he is proud of who he is while he is now happily in relation with his boyfriend. In addition of the two, there is another name that we must know: Charles Guislain. As the new fashion icon of Paris, he was named the next top fashion designer by Diane Parnet due to his unique taste. As a fashion icon who has feminine wardrobe, we can clearly sense the atmosphere of fashion is changing to unisexual trend.
Aside from male models who are active in female modeling industry, there are also female models who steal male models’ job due to their look. As one of the Chanel face, Saskia de Brauw is a model who plays both role well while she modeled for Saint Laurent Paris’ 2013 SS Men collection and the Prada 2013 SS collection around the same time. On the other hand, Casey Legler is a 100% female male model who had a contract with Ford Models. With her great physique from swimming for France in Olympic, she is exciting for her debut for 2013 FW fashion shows.
Lastly, there are two models must be mentioned for their braveness against the disease. For Stephen Thompson, the face of Givenchy in 2011, has Albinism, he has used his weakness to give fashion another shock sense of beauty. On the other hand, the 19 year old Louise Widderburn has the disease that might cause her life in the age of 41, but with the strong compassion on modeling, fashion world has opened the door for her by making her shine in 2013 SS London Fashion Week and Elle.««